Journal article

The association between mental disorders and suicide: A systematic review and meta-analysis of record linkage studies

Lay San Too, Matthew J Spittal, Lyndal Bugeja, Lennart Reifels, Peter Butterworth, Jane Pirkis

Journal of Affective Disorders | Elsevier | Published : 2019


Background: There has long been debate about the extent to which mental disorders contribute to suicide. We aimed to examine the evidence on the contribution of mental disorders to suicide among record linkage studies. Methods: We performed a systematic search using eight major health databases for English-language studies published between 1 January 2000 and 11 June 2018 that linked collected data on mental disorders and suicide. We then conducted a meta-analysis to assess risk of suicide conferred by mental disorders. Results: Our search identified 20 articles representing 13 unique studies. The pooled rate ratio (RR) was 13.2 (95% CI 8.6–20.3) for psychotic disorders, 12.3 (95% CI 8.9–1..

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Awarded by National Health and Medical Research Council

Awarded by Australian Research Council Future Fellowship

Funding Acknowledgements

This work was supported by Australian Government Department of Health, a National Health and Medical Research Council Senior Research Fellowship (grant no.: 1059261), an Australian Research Council Future Fellowship (grant no.: FT180100075), and a University of Melbourne Faculty of Medicine, Dentistry and Health Sciences Research Fellowship.