Synthesis, X-ray crystal structural, antioxidant and antibacterial studies of new Cu(II) macroacyclic Schiff base complex with a ligand containing homopiperazine moiety

Abstract

A symmetrical macroacyclic Schiff base ligand, L, has been prepared from the condensation of 2-((4-(2-aminobenzyl)-1,4-diazepan-1-yl)methyl) benzenamine (A) with 2-formylpyridine. Its copper complex was synthesized by the reaction of ligand with Cu(ClO4)2·6H2O in methanol. The characterization of the product by elemental analyses, IR, EI–MS, 1H and 13C NMR spectra, however, indicated that due to the structural preference of metal ion during the Schiff base formation equilibrium reaction, the metal was not coordinated by the expected N6 donor ligand, but only by an N5 donor ligand, where one of the azomethine groups of free ligand has been cleavaged to an NH2 group. This was also confirmed by..