Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium

Hannah A Pearce; Hongwei Qian; Timothy U Connell; Dexing Huang; Claudia Gottstein; Paul S Donnelly; Karlheinz Peter; Paul Gregorevic; Christoph E Hagemeyer

Journal article

Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium

Hannah A Pearce, Hongwei Qian, Timothy U Connell, Dexing Huang, Claudia Gottstein, Paul S Donnelly, Karlheinz Peter, Paul Gregorevic, Christoph E Hagemeyer

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT | CELL PRESS | Published : 2019

DOI: 10.1016/j.omtm.2019.07.003

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University of Melbourne Researchers

Hongwei Qian Author Physiology

Paul Donnelly Author Chemistry

Paul Gregorevic Author Physiology

Karlheinz Peter Author Baker Department of Cardiometabolic Health

Grants

Funding Acknowledgements

This work was funded by the National Health and Medical Research Council (NHMRC), the Australian Research Council (ARC), and the National Heart Foundation of Australia (NHF). The work was also supported in part by the Victorian Government's Operational Infra-structure Support Program. We thank Prof. Kleinschmidt for the anti-AAV producing hybridoma cell lines.