Visual loss and recovery in chiasmal compression
Helen V Danesh-Meyer, Jinny J Yoon, Mitchell Lawlor, Peter J Savino
Progress in Retinal and Eye Research | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019
Compression of the optic chiasm causes an optic neuropathy that may be associated with reversible visual loss often immediately following surgical decompression. While the precise pathogenesis of retinal ganglion cell impairment and eventual death remains poorly understood, a number of putative mechanisms may play a role. In this article we review the evidence supporting various stages of visual loss and recovery in chiasmal compression. These include conduction block, demyelination, ischemic insult, and retrograde and anterograde degeneration. We also describe novel advances in magnetic resonance imaging with specialized modalities such as diffusion tensor imaging have provided further info..View full abstract
This work was supported by the NAR foundation Optic Nerve Research Fellowship. We would like to thank Ms Jessica Kirton, our medical illustrator, for her contribution to this manuscript. The authors have no conflicts of interest to declare.