Journal article

Visual loss and recovery in chiasmal compression

Helen V Danesh-Meyer, Jinny J Yoon, Mitchell Lawlor, Peter J Savino

Progress in Retinal and Eye Research | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019


Compression of the optic chiasm causes an optic neuropathy that may be associated with reversible visual loss often immediately following surgical decompression. While the precise pathogenesis of retinal ganglion cell impairment and eventual death remains poorly understood, a number of putative mechanisms may play a role. In this article we review the evidence supporting various stages of visual loss and recovery in chiasmal compression. These include conduction block, demyelination, ischemic insult, and retrograde and anterograde degeneration. We also describe novel advances in magnetic resonance imaging with specialized modalities such as diffusion tensor imaging have provided further info..

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