TROG 18.01 phase III randomised clinical trial of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation: NINJA study protocol
Jarad Martin, Paul Keall, Shankar Siva, Peter Greer, David Christie, Kevin Moore, Jason Dowling, David Pryor, Peter Chong, Nicholas McLeod, Avi Raman, James Lynam, Joanne Smart, Christopher Oldmeadow, Colin I Tang, Declan G Murphy, Jeremy Millar, Keen Hun Tai, Lois Holloway, Penny Reeves Show all
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2019
INTRODUCTION: Stereotactic body radiotherapy (SBRT) is a non-invasive alternative to surgery for the treatment of non-metastatic prostate cancer (PC). The objectives of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation (NINJA) clinical trial are to compare two emerging SBRT regimens for efficacy with technical substudies focussing on MRI only planning and the use of knowledge-based planning (KBP) to assess radiotherapy plan quality. METHODS AND ANALYSIS: Eligible patients must have biopsy-proven unfavourable intermediate or favourable high-risk PC, have an Eastern Collaborative Oncology Group (ECOG) performance status 0-1 and provide written informe..View full abstract
Awarded by governmental Cancer Australia
This study underwent competitive peer review by the National Health and Medical Research Council (NHMRC) and was awarded governmental Cancer Australia funding (APP1158455). Additional seed funding was provided by mundipharma.