Using intermittent pulse oximetry to guide neonatal oxygen therapy in a low-resource context
Patrick James Berkeley Walker, Ayobami Adebayo Bakare, Adejumoke Idowu Ayede, Rosena Olubanke Oluwafemi, Omolayo Adebukola Olubosede, Iyabo Victoria Olafimihan, Kenneth Tan, Trevor Duke, Adegoke Gbadegesin Falade, Hamish Graham
Archives of Disease in Childhood: Fetal and Neonatal Edition | BMJ PUBLISHING GROUP | Published : 2020
OBJECTIVE: To evaluate the effectiveness of intermittent pulse oximetry in guiding oxygen therapy in neonates in a low-resource setting. DESIGN AND SETTING: Prospective validation study at three hospitals in southwest Nigeria. We performed concealed continuous pulse oximetry on participants to evaluate intermittent SpO2 monitoring. PATIENTS: We recruited all preterm or low birthweight neonates, and all term neonates who required oxygen therapy, who were admitted to the neonatal ward(s) of the study hospitals during the study period. MAIN OUTCOME MEASURES: Proportion of time preterm/low birthweight neonates on oxygen spent within, above and below the target SpO2 range of 90%-95%; and the prop..View full abstract
Awarded by Bill and Melinda Gates Foundation
The funders of the study include the Bill and Melinda Gates Foundation (financial support for the Nigeria Oxygen Implementation Project, in which this study is nested; OPP1123577), Masimo Corporation (provision of 10 Radical-7 CO-Oximeters, probes, and one Windows laptop computer) and the Murdoch Children's Research Institute ($A500 scholarship to support PJBW's involvement). All authors had full access to all the data in the study, and had final responsibility for the decision to submit for publication.