Conference Proceedings

Continuous bladder irrigation after transurethral resection of non-muscle invasive bladder cancer for prevention of tumour recurrence: a systematic review

Mo Li, Jason Toniolo, Ruchira Nandurkar, Nathan Papa, Nathan Lawrentschuk, Ian D Davis, Shomik Sengupta

ANZ JOURNAL OF SURGERY | WILEY | Published : 2021

Abstract

BACKGROUND: Non-muscle invasive bladder cancer (NMIBC) can recur despite transurethral resection of bladder tumour (TURBT) that clears macroscopic disease, partly from re-implantation of exfoliated cells. Immediate instillation of intravesical chemotherapy (IC) can reduce recurrence, is guideline-recommended but is under-utilized. Continuous bladder irrigation (CBI) immediately post-TURBT is postulated to prevent re-implantation, and may provide a simple, cheap and practical alternative. We undertook a systematic review to assess the effect of CBI on NMIBC recurrence. METHODS: Following PRISMA guidelines, relevant publications were identified by online search of databases, including Ovid Med..

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Grants

Awarded by NHMRC Practitioner Fellowship


Funding Acknowledgements

IDD is supported by an NHMRC Practitioner Fellowship (APP1102604).