Continuous bladder irrigation after transurethral resection of non-muscle invasive bladder cancer for prevention of tumour recurrence: a systematic review
Mo Li, Jason Toniolo, Ruchira Nandurkar, Nathan Papa, Nathan Lawrentschuk, Ian D Davis, Shomik Sengupta
ANZ JOURNAL OF SURGERY | WILEY | Published : 2021
BACKGROUND: Non-muscle invasive bladder cancer (NMIBC) can recur despite transurethral resection of bladder tumour (TURBT) that clears macroscopic disease, partly from re-implantation of exfoliated cells. Immediate instillation of intravesical chemotherapy (IC) can reduce recurrence, is guideline-recommended but is under-utilized. Continuous bladder irrigation (CBI) immediately post-TURBT is postulated to prevent re-implantation, and may provide a simple, cheap and practical alternative. We undertook a systematic review to assess the effect of CBI on NMIBC recurrence. METHODS: Following PRISMA guidelines, relevant publications were identified by online search of databases, including Ovid Med..View full abstract
Awarded by NHMRC Practitioner Fellowship
IDD is supported by an NHMRC Practitioner Fellowship (APP1102604).