Expression Profiling with cDNA Microarrays: A User’s Perspective and Guide

Abstract

Genomic science has now advanced to the point where it is possible to define the genomic structure and gene content of any organism. Such advances have led to the development of expression tools that can study gene expression in a massively parallel fashion. These methods are also affordable, sensitive, discriminating, and require minimal sample RNA. cDNA microarray expression profiling is a rapidly developing technology that makes possible monitoring of gene expression on a genome-wide scale.