Tag Sequencing

Abstract

Currently, technological advances in sequencing are revolutionizing the way in which genome‐scale biological research is performed. This is leading to an “explosion” of applications, made possible by the massive scale of data generated, and a similarly massive decrease in costs. Although any specific mention of throughputs, lengths, or costs will quickly become outdated as the technology is still rapidly evolving, the concepts and protocols surrounding the technology have largely stabilized. In this chapter, the technology, analysis, and common applications of tag sequencing will be explored, and an idea provided of how these will continue to impact on the major facets of nucleic acid resear..