Journal article

Associations of Health-Related Quality of Life, Fear of Falling and Objective Measures of Physical Function with Bone Health in Postmenopausal Women with Low Bone Mass

Anoohya Gandham, Lachlan B McMillan, Carrie-Anne Ng, Ludovic Humbert, Maxine P Bonham, Ayse Zengin, Peter R Ebeling, David Scott

JOURNAL OF CLINICAL MEDICINE | MDPI | Published : 2019

Abstract

Health-related quality of life (HRQoL) and physical function deteriorate with age and may adversely impact bone health in older adults. We determined associations of objective measures of physical function and HRQoL with bone health in postmenopausal women with low areal bone mineral density (aBMD). Fifty postmenopausal women (64.4 7.7 years old, mean standard deviation) with low spine, hip or femoral neck aBMD (T- or Z-score < -1.0) on dual-energy X-ray absorptiometry (DXA) participated. Femoral surface BMD, trabecular, integral and cortical volumetric BMD (vBMD) measurements were obtained using 3D-SHAPER software on DXA. Distal tibial vBMD and microarchitecture were assessed using high-res..

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University of Melbourne Researchers

Grants

Awarded by Monash University, Faculty of Medicine, Nursing and Health Sciences Strategic Grant


Awarded by NHMRC RD Wright Biomedical Career Development Fellowship


Funding Acknowledgements

This research was funded by Monash University, Faculty of Medicine, Nursing and Health Sciences Strategic Grant (SGS16-0388) awarded to D.S. D.S. is supported by a NHMRC RD Wright Biomedical Career Development Fellowship (GNT1123014).