Journal article

Information Processing by Simple Molecular Motifs and Susceptibility to Noise

Siobhan McMahon, Oleg Lenive, Sarah Filippi, Michael Stumpf

Published : 2015

Abstract

Biological organisms rely on their ability to sense and respond appropriately to their environment. The molecular mechanisms that facilitate these essential processes are however subject to a range of random effects and stochastic processes, which jointly affect the reliability of information transmission between receptors and e.g. the physiological downstream response. Information is mathematically defined in terms of the entropy; and the extent of information flowing across an information channel or signalling system is typically measured by the ``mutual information", or the reduction in the uncertainty about the output once the input signal is known. Here we quantify how extrinsic and int..

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University of Melbourne Researchers

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