Use of microaspiration to study the mechanical properties of polymer gel microparticles

Abstract

The mechanical properties of polyacrylamide (PA) and polydimethylsiloxane (PDMS) microparticle populations have been measured using microaspiration, a recently developed experimental technique. Microaspiration is an augmented version of micropipette aspiration, in which optical microscopy data are obtained as individual soft particles pass through the tip of a micropipette. During microaspiration, the ion current passing through the pipette tip is also measured, and the synchronised optical and current data streams are used to study and quantify mechanical properties. Ion current signatures for the poroelastic PA particles were qualitatively different from those of the viscoelastic PDMS part..