Journal article
Extracting more for less: multi-echo MP2RAGE for simultaneous T1-weighted imaging, T1 mapping, R2∗ mapping, SWI, and QSM from a single acquisition
H Sun, JO Cleary, R Glarin, SC Kolbe, RJ Ordidge, BA Moffat, GB Pike
Magnetic Resonance in Medicine | WILEY | Published : 2020
DOI: 10.1002/mrm.27975
Abstract
Purpose: To demonstrate simultaneous T1-weighted imaging, T1 mapping, (Formula presented.) mapping, SWI, and QSM from a single multi-echo (ME) MP2RAGE acquisition. Methods: A single-echo (SE) MP2RAGE sequence at 7 tesla was extended to ME with 4 bipolar gradient echo readouts. T1-weighted images and T1 maps calculated from individual echoes were combined using sum of squares and averaged, respectively. ME-combined SWI and associated minimum intensity projection images were generated with TE-adjusted homodyne filters. A QSM reconstruction pipeline was used, including a phase-offsets correction and coil combination method to properly combine the phase images from the 32 receiver channels. Meas..
View full abstractGrants
Awarded by Alberta Innovates - Health Solutions
Funding Acknowledgements
This work was supported by grants from Alberta Innovates Health Solutions; Canadian Institutes of Health Research (grant FDN-143290); Campus Alberta Innovates Program; Australian National Imaging Facility funded by National Collaborative Research Infrastructure Strategy; University of Melbourne McKenzie Fellowship; National Health and Medical Research Council Peter Doherty Fellowship; and the Rebecca Hotchkiss International Scholar Exchange Hotchkiss Brain Institute-Melbourne Trainee Research Exchange Program.