Journal article

Angiographic Outcome of Coronary Artery Bypass Grafts: The Radial Artery Database International Alliance

Mario Gaudino, Umberto Benedetto, Stephen E Fremes, David L Hare, Philip Hayward, Neil Moat, Marco Moscarelli, Antonino Di Franco, Giuseppe Nasso, Miodrag Peric, Ivana Petrovic, Peter Collins, Carolyn M Webb, John D Puskas, Giuseppe Speziale, Kyung Jong Yoo, Leonard N Girardi, David P Taggart



BACKGROUND: We used a large patient-level data set including 6 angiographic randomized controlled trials (RCTs) on coronary artery bypass conduits to explore incidence and determinants of coronary graft failure. METHODS: Patient-level angiographic data of 6 RCTs comparing long-term outcomes of the radial artery and other conduits were joined. Primary outcome was graft occlusion at maximum follow-up. The analysis was divided as (1) left anterior descending coronary (LAD) distribution and (2) non-LAD distribution (circumflex and right coronary artery). Mixed-model multivariable Cox regression including all baseline characteristics with stratification by individual trials was used to identify p..

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Funding Acknowledgements

The project was funded by the Department of Cardiothoracic Surgery of Weill Cornell Medicine. Umberto Benedetto was supported by The National Institute for Health Research Bristol Biomedical Research Centre. Stephen E. Fremes was supported in part by the Bernard S. Goldman Chair in Cardiovascular Surgery. Support was also provided by a grant from the Victor Phillip Dahdaleh Charitable Foundation held by Peter Collins. David L. Hare received research funds from Servier. The funders had no role in any part the study.