Functional Measures of Sarcopenia: Prevalence, and Associations with Functional Disability in 10,892 Adults Aged 65 Years and Over from Six Lower- and Middle-Income Countries
Sharon L Brennan-Olsen, Steven J Bowe, Paul Kowal, Nirmala Naidoo, Nekehia T Quashie, Geeta Eick, Sutapa Agrawal, Catherine D'Este
CALCIFIED TISSUE INTERNATIONAL | SPRINGER | Published : 2019
Identification of sarcopenia in lower- and middle-income countries (LMICs) is limited by access to technologies that assess muscle mass. We investigated associations between two functional measures of sarcopenia, grip strength and gait speed (GS), with functional disability in adults from six LMICs. Data were extracted from the World Health Organization (WHO) Study on global AGEing and adult health Wave 1 (2007-2010) for adults (≥ 65 years) from China, Mexico, Ghana, India, Russia and South Africa (n = 10,892, 52.8% women). We calculated country-specific prevalence of low grip strength, slow GS (≤ 0.8 m/s), and both measures combined. Using multivariable negative binomial regression, we sepa..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC) of Australia
Awarded by Division of Behavioral and Social Research (BSR) at the US National Institute on Aging (NIA)
SLB-O is the recipient of a Career Development Fellowship from the National Health and Medical Research Council (NHMRC) of Australia (1107510). SAGE is supported by WHO and the Division of Behavioral and Social Research (BSR) at the US National Institute on Aging (NIA) through interagency agreements (OGHA 04034785; YA1323-08-CN-0020; Y1-AG-1005-01) with WHO. In addition, the governments of Shanghai, China and South Africa provided financial or other support for Wave 1 of their national SAGE study. All collaborating institutions provided substantial resources to conduct their respective studies. We thank the participants in each country for their contributions to SAGE and acknowledge the contributions and expertise of the country-specific investigators and their respective survey teams. We acknowledge the intellectual input of Dr Jesse Zanker and Mr Steven Phu regarding recommended measurement of, and cut-points for, gait speed and grip strength in terms of sarcopenia assessment.