Associations between sleep and verbal memory in subjective cognitive decline: A role for semantic clustering
Jessica E Manousakis, Christian Nicholas, Anna J Scovelle, Sharon L Naismith, Clare Anderson
Neurobiology of Learning and Memory | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2019
Age-related reductions in slow wave activity (SWA) and increased fragmentation during sleep play a key role in memory impairment. As the prefrontal cortex is necessary for the control processes relevant to memory encoding, including utilisation of internal heuristics such as semantic clustering, and is preferentially vulnerable to sleep disturbance, our study examined how SWA and sleep fragmentation relates to memory performance in individuals with Subjective Cognitive Decline (SCD). Thirty older adults with SCD (Mean Age = 69.34, SD = 5.34) completed a neurocognitive test battery, including the California Verbal Learning Test, which was used to assess semantic clustering. One week later, pa..View full abstract
Awarded by ANZ Trustees
This study was funded by the Mason Foundation, ANZ Trustees (grant number CT23151 awarded to CA and SLN). JEM and AJS were supported by an Australian Government Research Training Program Scholarship. JEM also received a scholarship from the NHMRC Centre of Research Excellence Neurosleep. SLN is supported by an NHMRC Dementia Leadership Fellowship.