Lgr(5 ) pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

Chow Hiang Ang; Shih Han Hsu; Fusheng Guo; Chong Teik Tan; Victor C Yu; Jane E Visvader; Pierce KH Chow; Nai Yang Fu

Journal article

Lgr(5 ) pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

Chow Hiang Ang, Shih Han Hsu, Fusheng Guo, Chong Teik Tan, Victor C Yu, Jane E Visvader, Pierce KH Chow, Nai Yang Fu

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2019

DOI: 10.1073/pnas.1908099116

University of Melbourne Researchers

Nai Fu Author Medical Biology (W.E.H.I.)

Jane Visvader Author Medical Biology (W.E.H.I.)

Grants

Funding Acknowledgements

We thank the veterinarians, animal technicians, and staffs from FACS and Advance Bioimaging facilities at Duke-NUS and SingHealth for their technical support. We give special thanks to E.S. Leman for critical reading and insightful comments on the manuscript. C.H.A. is supported by Khoo Postdoctoral Fellowship Award. This work was supported by Duke-NUS Faculty Start-up Fund and Khoo Bridge Funding Award.