Journal article

Five-year changes in anterior segment parameters in an older population in urban southern China: the Liwan Eye Study

Yu Jiang, Decai Wang, Wei Wang, Feng Chen, Lanhua Wang, Jane Scheetz, Wenyong Huang, Shengsong Huang, Mingguang He

British Journal of Ophthalmology | BMJ PUBLISHING GROUP | Published : 2020


PURPOSE: To investigate the 5-year changes in static and dynamic anterior segment optical coherence tomography (AS-OCT) parameters and their predictors. METHODS: This was a prospective, population-based cohort study of people aged 50 years and older residing in the Liwan District, Guangzhou, China. Standardised AS-OCT scans were performed in November 2008 and November 2013 under dark and light conditions. Customised software was used to analyse horizontal AS-OCT images. Parameters in dark and measurements of light-to-dark changes were used for analyses. RESULTS: A total of 186 (71.8%) subjects underwent AS-OCT twice, 5 years apart and were included for analyses. The mean age in 2008 was 64.7..

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University of Melbourne Researchers


Awarded by National Natural Science Foundation of China

Awarded by Science and Technology Planning Project of Guangdong Province, China

Funding Acknowledgements

This research was supported in part by the grant from the Fundamental Research Funds of the State Key of Ophthalmology, National Natural Science Foundation of China (81420108008 81570843H1204), Science and Technology Planning Project of Guangdong Province, China (2013B20400003). MH receives support from the University of Melbourne at Research Accelerator Program and the CERA Foundation. The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian State Government. No additional external funding was received.