Journal article

The impact of morphological characteristics on late outcomes in patients born with hypoplastic left heart syndrome

David P Newland, Chin L Poh, Diana Zannino, Patrick Elias, Christian P Brizard, Kirsten Finucane, David S Winlaw, Yves d'Udekem

European Journal of Cardio-Thoracic Surgery | OXFORD UNIV PRESS INC | Published : 2019

Abstract

OBJECTIVES: Patients with hypoplastic left heart syndrome are at high risk of late adverse events after Fontan completion, but it is unclear whether their morphological characteristics influence these outcomes. METHODS: Retrospective review of the data from the Australian and New Zealand Fontan Registry identified 185 patients with hypoplastic left heart syndrome who survived to hospital discharge after Fontan completion. Their outcomes were reviewed to identify predictors of adverse events with a particular focus on the impact of morphological characteristics. All available echocardiographic parameters were collected, and the hypoplasia of the left ventricle was subjectively considered to b..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by National Heart Foundation Australia Program


Awarded by NHMRC


Funding Acknowledgements

This work was supported by a National Health and Medical Research Council (NHMRC) Partnership Grant [1076849]. The contents of the published material are solely the responsibility of the individual authors. Yves d'Udekem is a Career Development Fellow of The National Heart Foundation Australia Program [CR 10M 5339] and NHMRC Clinical Practitioner Fellow [1082186].