The relationship between microstructure, stiffness and compressive fatigue life of equine subchondral bone
Sandra Martig, Peta L Hitchens, Peter VS Lee, R Chris Whitton
Journal of The Mechanical Behavior of Biomedical Materials | Elsevier | Published : 2020
Subchondral bone injuries often precede articular cartilage damage in osteoarthritis and are common in thoroughbred racehorses due to the accumulation of fatigue damage from high speed racing and training. Thus, racehorses provide a model to investigate the role of subchondral bone in joint disease. We assessed the association of horse and racing related factors and micro-CT based micromorphology of three separate subchondral bone layers with the initial stiffness and compressive fatigue life of bone plugs. Furthermore, we investigated three different definitions of fatigue failure of subchondral bone during compressive fatigue testing. Initial stiffness was 2,362 ± 443 MPa (mean ± standard ..View full abstract
Sandra Martig was supported by an Australian Government Research Training Program Scholarship. The micro-CT examinations were supported by a grant from the ANZ Kathleen Agnes Back Estate. Peta Hitchens and Chris Whitton were supported by funding from Racing Victoria Limited, the Victorian Racing Industry Fund of the Victorian State Government, and The University of Melbourne.