Journal article
Clinical depression in untreated obstructive sleep apnea: examining predictors and a meta-analysis of prevalence rates
ML Jackson, J Tolson, D Bartlett, DJ Berlowitz, P Varma, M Barnes
Sleep Medicine | ELSEVIER | Published : 2019
Abstract
Objective/background: Patients with obstructive sleep apnea (OSA) experience daytime sleepiness, cognitive impairment and depressive symptoms. However, the measured prevalence of clinical depression in OSA using standardized clinical assessment is currently unclear. The aims of this study were to examine the prevalence of clinical depression and antidepressant use in untreated OSA patients, to examine predictors of depression, and to conduct an exploratory meta-analysis to determine the pooled prevalence of clinical depression in this population. Patients/methods: In sum, 109 consecutive patients with diagnosed OSA (mean age (SD) = 52.6 (12.1) years; 43.1% female) who presented to the sleep ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study was funded by the Austin Medical Research Fund. MLJ was supported by an NHMRC Early Career Fellowship (APP1036292). CPAP devices used in the next phase of this study were provided by Air Liquide. Air Liquide had no role in study design, analysis or in manuscript preparation. The authors have no conflicts of interest to declare. The study was conducted in the Department of Respiratory and Sleep Medicine, Austin Health, Melbourne.