Journal article

Does vaccination with the live mycoplasma vaccine MSH increase the pathogenicity of Avian influenza infections?

Chris J Morrow

Poultry Science | Oxford University Press (OUP) | Published : 2020


In the 2017 paper “Mycoplasma synoviae vaccine modifies virus shedding and immune responses of avian influenza (H9N2) infection in commercial layers” (Umar et al., 2017) authors describe experiments in Pakistan where H9N2 infection parameters were modified by vaccination with the live Mycoplasma synoviae (MS) vaccine MSH. This outcome is conceivable and could possibly be a downside of live vaccination, but the results are presented as though they are a unique property of the vaccine without considering that field strains might also possess these properties (possibly with greater effect). Indeed, mycoplasma species and other respiratory tract microbiota considered to be commensals may also be..

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University of Melbourne Researchers