Journal article

Pneumococcal conjugate vaccine use during humanitarian crises

Kevin van Zandvoort, Francesco Checchi, Emma Diggle, Rosalind M Eggo, Kartini Gadroen, Kim Mulholland, Catherine R McGowan, Olivier le Polain de Waroux, V Bhargavi Rao, Catherine Satzke, Stefan Flasche

Vaccine | ELSEVIER SCI LTD | Published : 2019

Abstract

Streptococcus pneumoniae is a common human commensal that causes a sizeable part of the overall childhood mortality in low income settings. Populations affected by humanitarian crises are at especially high risk, because a multitude of risk factors that are enhanced during crises increase pneumococcal transmission and disease severity. Pneumococcal conjugate vaccines (PCVs) provide effective protection and have been introduced into the majority of routine childhood immunisation programmes globally, though several barriers have hitherto limited their uptake during humanitarian crises. When PCV coverage cannot be sustained during crises or when PCV has not been part of routine programmes, mass..

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Grants

Awarded by Sir Henry Dale Fellowship - Wellcome Trust


Awarded by Sir Henry Dale Fellowship - Royal Society


Awarded by HDR UK Innovation Fellowship


Awarded by Australian NHMRC Career Development Fellowship


Funding Acknowledgements

KvZ, FC, CS and KM are supported by Elrha's Research for Health in Humanitarian Crises (R2HC) Programme, which aims to improve health outcomes by strengthening the evidence base for public health interventions in humanitarian crises. The R2HC programme is funded by the UK Government (DFID), the Wellcome Trust, and the UK National Institute for Health Research (NIHR).SF was supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and Royal Society (grant number 208812/Z/17/Z). RME acknowledges funding from an HDR UK Innovation Fellowship (grant MR/S003975/1).CS is supported by an Australian NHMRC Career Development Fellowship (1087957) and a Veski Inspiring Women Fellowship. MCRI is supported by the Victorian Government's Operational Infrastructure Support Program.The UK Public Health Rapid Support Team is funded by the National Institute for Health Research and the Department of Health and Social Care. The views expressed are those of the authors and not necessarily those of the NIHR or DHSC.