Dose to medium in head and neck radiotherapy: Clinical implications for target volume metrics
Nicholas Hardcastle, Atousa Montaseri, Jenny Lydon, Tomas Kron, Glen Osbourne, Georgina Casswell, David Taylor, Lisa Hall, Lachlan McDowell
PHYSICS & IMAGING IN RADIATION ONCOLOGY | ELSEVIER | Published : 2019
Background and purpose: In radiotherapy dose calculation, advanced type-B dose calculation algorithms can calculate dose to medium (Dm ), as opposed to Type-B algorithms which compute dose to varying densities of water (Dw ). We investigate the impact of Dm on calculated dose and target coverage metrics in head and neck cancer patients. Methods and materials: We reviewed 27 successfully treated (disease free at two-years post-(chemo)radiotherapy) human papillomavirus-associated (HPV) oropharyngeal cancer (ONC) patients treated with IMRT. Doses were calculated with Type-B and Linear Boltzman Transport Equation (LBTE) algorithms in a commercial treatment planning system, with the treated multi..View full abstract
The Peter MacCallum Cancer Centre Foundation for support for this research.