Journal article
A high-volume, low-cost approach to participant screening and enrolment: Experiences from the T4DM diabetes prevention trial
K Bracken, A Keech, W Hague, C Allan, A Conway, M Daniel, V Gebski, M Grossmann, DJ Handelsman, WJ Inder, A Jenkins, R McLachlan, KP Robledo, B Stuckey, BB Yeap, G Wittert
Clinical Trials | SAGE PUBLICATIONS LTD | Published : 2019
Abstract
Background/aims: Participant recruitment to diabetes prevention randomised controlled trials is challenging and expensive. The T4DM study, a multicentre, Australia-based, Phase IIIb randomised controlled trial of testosterone to prevent Type 2 diabetes in men aged 50–74 years, faced the challenge of screening a large number of prospective participants at a small number of sites, with few staff, and a limited budget for screening activities. This article evaluates a high-volume, low-cost, semi-automated approach to screen and enrol T4DM study participants. Methods: We developed a sequential multi-step screening process: (1) web-based pre-screening, (2) laboratory screening through a network o..
View full abstractGrants
Awarded by Eli Lilly and Company
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported through National Health and Medical Research Council (NHMRC) Project Grant (No. 030123), Bayer, Lilly, and University of Adelaide. Weight Watchers provided enrolment to their programme for trial participants without cost. K.B. was supported by a postgraduate scholarship from the NHMRC Clinical Trials Centre, University of Sydney.