Journal article
Interval breast cancer risk associations with breast density, family history and breast tissue aging
Tuong L Nguyen, Shuai Li, Gillian S Dite, Ye K Aung, Christopher F Evans, Ho N Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Dallas R English, Mark A Jenkins, Pierre-Antoine Dugue, Roger L Milne, Melissa C Southey, Graham G Giles, Malcolm C Pike, John L Hopper
INTERNATIONAL JOURNAL OF CANCER | WILEY | Published : 2019
DOI: 10.1002/ijc.32731
Abstract
Interval breast cancers (those diagnosed between recommended mammography screens) generally have poorer outcomes and are more common among women with dense breasts. We aimed to develop a risk model for interval breast cancer. We conducted a nested case-control study within the Melbourne Collaborative Cohort Study involving 168 interval breast cancer patients and 498 matched control subjects. We measured breast density using the CUMULUS software. We recorded first-degree family history by questionnaire, measured body mass index (BMI) and calculated age-adjusted breast tissue aging, a novel measure of exposure to estrogen and progesterone based on the Pike model. We fitted conditional logistic..
View full abstractRelated Projects (4)
Grants
Awarded by Australian National Health and Medical Research Council
Awarded by Cure Cancer Australia - Cancer Australia
Awarded by US National Institutes of Health/National Cancer Institute Cancer Institute
Awarded by National Breast Cancer Foundation
Funding Acknowledgements
Grant sponsor: Australian National Health and Medical Research Council; Grant numbers: 1074383, 209057, 251533, 396414, 504711; Grant sponsor: Cure Cancer Australia - Cancer Australia; Grant number: 1159399; Grant sponsor: US National Institutes of Health/National Cancer Institute Cancer Institute; Grant number: P30CA008748