Journal article
Perspectives on Analytical Treatment Interruptions in People Living with HIV and Their Health Care Providers in the Landscape of HIV Cure-Focused Studies
JSY Lau, MZ Smith, B Allan, C Martinez, J Power, SR Lewin, JH McMahon
AIDS Research and Human Retroviruses | MARY ANN LIEBERT, INC | Published : 2020
Abstract
Analytical treatment interruptions (ATIs) aim to assess effects of HIV cure-focused interventions, but poses potential risks. Understanding of ATI acceptability among people living with HIV (PLHIV) and their HIV health care providers (HHP) is limited. Two international online surveys for PLHIV and HHP assessed understanding and acceptability of monitoring strategies during ATI. Survey items included the following: frequency of CD4, viral load (VL) and clinical assessment, CD4 and VL threshold to restart antiretroviral therapy (ART), acceptability of detectable viremia during ATI, and potential risks of ATI. Responses were collected from July 2017 to January 2018, and a descriptive analysis w..
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Awarded by National Institute of Allergy and Infectious Diseases
Funding Acknowledgements
The institution of James H. McMahon and Jillian S.Y. Lau receive funding from Gilead Sciences, ViiV Healthcare, Merck, and Shire to conduct clinical trials. Jillian S.Y. Lau has an NHMRC Postgraduate Scholarship (1151607). James H. McMahon has an NHMRC Early Career Fellowship (1111099). Sharon R. Lewin is an NHMRC Practitioner Fellow (1042654) and is supported by the National Institutes of Health Delaney AIDS Research Enterprise (UM1 AI12661101) and the American Foundation for AIDS Research (109226-58 RGRL).