Journal article
Comparable effects of nicotine in smokers and nonsmokers on a prospective memory task
Jennifer M Rusted, Steven Trawley
NEUROPSYCHOPHARMACOLOGY | NATURE PUBLISHING GROUP | Published : 2006
Abstract
In a double-blind placebo-controlled study, we examined the effect of nicotine, a cholinergic agonist, on performance of a prospective memory (ProM) task in young adult volunteers. Volunteers were required to complete an ongoing lexical decision task while maintaining the ProM task (responding with a different button press to items containing particular target letters). Half of the volunteers were smokers, half were nonsmokers. Half of each group received a single dose (1 mg) of nicotine nasal spray before completing the task; the remaining volunteers received a matched inactive placebo spray. Nicotine improved performance on the ProM task when volunteers were able to devote resources to tha..
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