Journal article

Opioid use prior to elective surgery is strongly associated with persistent use following surgery: an analysis of 14 354 Medicare patients

Max Catchpool, Josh Knight, Jesse T Young, Philip Clarke, Michael J Barrington, Peter FM Choong, Michelle M Dowsey

ANZ Journal of Surgery | WILEY | Published : 2019

Abstract

BACKGROUND: Persistent opioid use following total joint replacement (TJR) surgery is common; however, the association between pre-surgical opioid use and surgery type has not been established. The objective of this study was to determine the association between pre-surgery opioid use and persistent post-surgery opioid use in TJR patients compared to other elective surgical patients. METHODS: This is a retrospective cohort study, of univariate and multinomial logistic regression of linked, de-identified Medicare Benefits Schedule and Pharmaceutical Benefits Schedule data, adjusted for perioperative opioid use, age and sex. Oral morphine equivalents daily doses (OMEDD) were calculated and opio..

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Grants

Awarded by National Health and Medical Research Council Centre for Research Excellence in Total Joint Replacement OPtimising oUtcomes, equity, cost effectiveness and patient Selection (OPUS)


Awarded by Centre of Excellence in Population Ageing Research, Australian Research Council (CEPAR)


Awarded by NHMRC


Funding Acknowledgements

This research was supported by the National Health and Medical Research Council Centre for Research Excellence in Total Joint Replacement OPtimising oUtcomes, equity, cost effectiveness and patient Selection (OPUS) (APP1116325). JK and PC were supported by the Centre of Excellence in Population Ageing Research, Australian Research Council (CEPAR) (CE170100005). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. MMD holds an NHMRC Career Development Fellowship (APP1122526). PFMC holds an NHMRC Practitioner Fellowship (APP1154203).