Controversies in Diagnosing Sarcopenia in Cirrhosis-Moving from Research to Clinical Practice
Nutrients | MDPI | Published : 2019
Sarcopenia, defined as loss of muscle mass and function, is increasingly recognized as a common consequence of advanced cirrhosis that is associated with adverse clinical outcomes. Despite the recent proliferation in publications pertaining to sarcopenia in end-stage liver disease, there remains no single 'best method' for its diagnosis. The inability to identify a gold standard is common to other specialties, including geriatrics from which many diagnostic tools are derived. Controversies in diagnosis have implications for the accuracy and reproducibility of cohort studies in the field, largely prohibit the introduction of sarcopenia measurement into routine patient care and impede the deve..View full abstract
The completion of this work was aided by the receipt of a National Health and Medical Research Council (NHMRC) Early Career Fellowship awarded to Marie Sinclair.