Journal article

Acute Toxoplasma infection in pregnant women worldwide: A systematic review and meta-analysis

Ali Rostami, Seyed Mohammad Riahi, Despina G Contopoulos-Ioannidis, H Ray Gamble, Yadolah Fakhri, Malihe Nourollahpour Shiadeh, Masoud Foroutan, Hamed Behniafar, Ali Taghipour, Yvonne A Maldonado, Ali H Mokdad, Robin B Gasser

PLOS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2019

Abstract

BACKGROUND: Acute Toxoplasma infection (ATI) during pregnancy, if left untreated, can cause severe adverse outcomes for the fetus and newborn. Here, we undertook a meta-analysis to estimate the worldwide prevalence of ATI in pregnant women. METHODS: We searched international databases for studies published between January 1988 and November 2018. We included population-based cross-sectional and prospective cohort studies that reported the prevalence of ATI in pregnant women. Data were synthesized using a random effect model to calculate the overall prevalence of ATI (with a 95% CI) in six WHO regions and globally. We also performed linear meta-regression analyses to investigate associations o..

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University of Melbourne Researchers