Maternal obesity and gestational diabetes decrease Metrnl concentrations in cord plasma.
The Journal of Maternal-Fetal & Neonatal Medicine | Published : 2019
Objective: To determine the effect of preexisting maternal obesity and gestational diabetes mellitus (GDM) on the circulating levels of Metrnl in cord and maternal plasma. Design: Metrnl levels were measured on maternal and cord plasma from women with normal glucose tolerance (NGT) (19 non-obese and 20 obese), GDM controlled by diet (18 non-obese and 17 obese) and GDM controlled by insulin (19 non-obese and 18 obese) at the time of term elective cesarean section. Metrnl concentrations were determined by enzyme-linked immunoassay. Correlations of Metrnl levels with anthropometric parameters and laboratory measurements were also assessed. Results: There was no effect of maternal obesity or GDM..View full abstract