Journal article
Bilateral hypoglossal nerve stimulation for treatment of adult obstructive sleep apnoea
PR Eastwood, M Barnes, SG MacKay, JR Wheatley, DR Hillman, XL Nguyên, R Lewis, MC Campbell, B Pételle, JH Walsh, AC Jones, CE Palme, A Bizon, N Meslier, C Bertolus, KJ Maddison, L Laccourreye, G Raux, K Denoncin, V Attali Show all
European Respiratory Journal | EUROPEAN RESPIRATORY SOC JOURNALS LTD | Published : 2020
Abstract
Background and aim: Hypoglossal nerve stimulation (HNS) decreases obstructive sleep apnoea (OSA) severity via genioglossus muscle activation and decreased upper airway collapsibility. This study assessed the safety and effectiveness at 6 months post-implantation of a novel device delivering bilateral HNS via a small implanted electrode activated by a unit worn externally, to treat OSA: the Genio™ system. Methods: This prospective, open-label, non-randomised, single-arm treatment study was conducted at eight centres in three countries (Australia, France and the UK). Primary outcomes were incidence of device-related serious adverse events and change in the apnoea-hypopnoea index (AHI). The sec..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study trial was funded by Nyxoah S.A. P.R. Eastwood is funded by a National Health and Medical Research Council Senior Research Fellowship (number 1136548). S.G. MacKay is a Chief Investigator on National Health and Medical Research Council of Australia Grant, 1059510; Australian New Zealand Clinical Trials Registry ACTRN12614000338662 and a Chief Investigator on a Garnett Passe Rodney Williams Foundation Conjoint Grant.