Journal article

Peak Creatinine, Cardiopulmonary Bypass, and Mortality After Stage 1 Single-Ventricle Reconstruction

Andrew Girgis, Johnny Millar, Warwick Butt, Yves d'Udekem, Siva P Namachivayam

The Annals of Thoracic Surgery | ELSEVIER SCIENCE INC | Published : 2020


BACKGROUND: Serum creatinine is the most commonly used marker to diagnose acute kidney injury. Studies exploring creatinine patterns in the single-ventricle population are scarce. We studied serum creatinine up to 5 postoperative days after the stage 1 operation and assessed its relationship with outcomes. METHODS: Neonates who underwent a first-stage single-ventricle operation (Norwood or a Damus-Kaye-Stansel) between 2005 and 2017 were retrospectively analyzed. Peak percentage creatinine change (PPCC) was defined as the difference between the baseline (preoperative) and the peak postoperative level (within 5 postoperative days), expressed as a percentage of the baseline level. RESULTS: Amo..

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Awarded by National Heart Foundation of Australia

Funding Acknowledgements

The authors wish to thank Dr Tom Scodellaro for providing them with study data and research coordinators of the Audit and Data Research Team in the Paediatric Intensive Care Unit of RCH Melbourne. Dr Siva Namachivayam is supported by a health professional research scholarship (award No. 101003) from the National Heart Foundation of Australia.