Variation in menopausal vasomotor symptoms outcomes in clinical trials: A systematic review
S Iliodromiti, W Wang, MA Lumsden, MS Hunter, R Bell, G Mishra, M Hickey
BJOG: an International Journal of Obstetrics and Gynaecology | WILEY | Published : 2019
BACKGROUND: There is substantial variation in how menopausal vasomotor symptoms are reported and measured among intervention studies. This has prevented meaningful comparisons between treatments and limited data synthesis. OBJECTIVES: To review systematically the outcome reporting and measures used to assess menopausal vasomotor symptoms from randomised controlled trials of treatments. SEARCH STRATEGY: We searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials from inception to May 2018. SELECTION CRITERIA: Randomised controlled trials with a primary outcome of menopausal vasomotor symptoms in women and a sample size of at least 20 women per study arm. DATA COLLECTION AN..View full abstract
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Awarded by MRC
Awarded by NHMRC
This study was funded by an MRC postdoctoral fellowship (S.I., MR/N015177/1), NHMRC Practitioner Fellowship (M.H., APP 1058935), and an NHMRC Principal Research Fellowship (G.D.M., APP1121844). The funders were not involved in any stage of this systematic review.