Variation in menopausal vasomotor symptoms outcomes in clinical trials: A systematic review
S Iliodromiti, W Wang, MA Lumsden, MS Hunter, R Bell, G Mishra, M Hickey
BJOG: an International Journal of Obstetrics and Gynaecology | WILEY | Published : 2019
BACKGROUND: There is substantial variation in how menopausal vasomotor symptoms are reported and measured among intervention studies. This has prevented meaningful comparisons between treatments and limited data synthesis. OBJECTIVES: To review systematically the outcome reporting and measures used to assess menopausal vasomotor symptoms from randomised controlled trials of treatments. SEARCH STRATEGY: We searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials from inception to May 2018. SELECTION CRITERIA: Randomised controlled trials with a primary outcome of menopausal vasomotor symptoms in women and a sample size of at least 20 women per study arm. DATA COLLECTION AN..View full abstract
Awarded by MRC
Awarded by NHMRC
This study was funded by an MRC postdoctoral fellowship (S.I., MR/N015177/1), NHMRC Practitioner Fellowship (M.H., APP 1058935), and an NHMRC Principal Research Fellowship (G.D.M., APP1121844). The funders were not involved in any stage of this systematic review.