Conference Proceedings
Normative retrobulbar measurements of the optic nerve using ultra high field magnetic resonance imaging
Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick
Investigative Ophthalmology and Visual Science | Association for Research in Vision and Ophthalmology | Published : 2019
Abstract
Purpose : We exploit the improved spatial resolution and signal-to-noise gain of ultra high field (7T) magnetic resonance imaging (MRI) with a dedicated eye coil for more accurate morphometric measurements of the optic nerve ~2.5mm behind the globe. Methods : Coronal T2-weighted oblique images (TR=2000ms, TE=64ms, FOV=155mm, matrix=384 x 384, slice thickness=0.7mm, scan time=2’34”) through the optic nerve were obtained in 21 healthy adults (20-41 years, 11 emmetropes: +0.75 to -0.50D, 10 myopes: -4.5 to -12D) using a 7T Siemens Magnetom scanner (Erlangen, Germany) and 6-channel eye coil (MRI.TOOLS GmbH, Berlin, Germany). Horizontal and vertical outer diameter of the optic nerve, subarachnoi..
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Funding Acknowledgements
Melbourne Neuroscience Institute Fellowship (BNN), University of Melbourne Mackenzie Fellowship (JOC), Melbourne Neuroscience Institute Interdisciplinary Seed Funding Grant (AMM, BVB, RJO). The 7T system at MBCIU is supported by the Australian National Imaging Facility.