Improved visual acuity using a retinal implant and an optimized stimulation strategy
Wei Tong, Melanie Stamp, Nicholas Apollo, Kumaravelu Ganesan, Hamish Meffin, Steven Prawer, David J Garrett, Michael R Ibbotson
Journal of Neural Engineering | IOP PUBLISHING LTD | Published : 2020
OBJECTIVE: Retinal prosthetic devices hold great promise for the treatment of retinal degenerative diseases such as retinitis pigmentosa and age-related macular degeneration. Through electrical stimulation of the surviving retinal neurons, these devices evoke visual signals that are then relayed to the brain. Currently, the visual prostheses used in clinical trials have few electrodes, thus limiting visual acuity. Electrode arrays with high electrode densities have been developed using novel technologies, including diamond growth and laser machining, and these may provide a more promising route to achieve high visual acuity in blind patients. APPROACH: Here, we studied the potential spatial ..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) of Australia
Awarded by NHMRC
We thank the Melbourne Advanced Microscopy Facility housed within Bio21 at The University of Melbourne for SEM Imaging. The research was supported by a Development Grant from The National Health and Medical Research Council (NHMRC, GNT1118223) of Australia. The work was performed in part at the Melbourne Centre for Nanofabrication (MCN) in the Victorian Node of the Australian National Fabrication Facility (ANFF). DJG is supported by NHMRC Project Grant GNT1101717 and by an Australian Nanofabrication Facility (ANFF)/Melbourne Centre for Nanofabrication (MCN) Technology Ambassador Fellowship. SP is cofounder and shareholder of iBIONICS, a company developing a diamond based retinal prothesis. SP, DJG and NVA are shareholders and executive officers of Carbon Cybernetics Pty Ltd, a company developing diamond and carbon-based medical device components. The other authors declare no conflict of interest.