Health outcomes of iron supplementation and/or food fortification in iron-replete children aged 4-24 months: protocol for a systematic review and meta-analysis
Dominic J Hare, Sabine Braat, Barbara R Cardoso, Christopher Morgan, Ewa A Szymlek-Gay, Beverley-Ann Biggs
Systematic Reviews | BioMed Central | Published : 2019
BACKGROUND: Direct supplementation or food fortification with iron are two public health initiatives intended to reduce the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) in 4-24-month-old infants. In most high-income countries where IDA prevalence is 40%. Emerging concerns about delayed neurological effects of early-life iron overexposure have raised questions as to whether recommended guidelines in high-income countries are unnecessarily excessive. This systematic review will gather evidence from supplementation/fortification trials, comparing health outcomes in studies where iron-replete children did or did not receive additional dietary iron; and determine if reple..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
This study is funded as part of a National Health and Medical Research Council (NHMRC) Career Development Fellowship to DJH (GNT1122981). The NHMRC has had no role in protocol design.