Journal article

Bony stress in the lumbar spine is associated with intervertebral disc degeneration and low back pain: a retrospective case-control MRI study of patients under 25 years of age

Daniel Chepurin, Uphar Chamoli, Kyle Sheldrick, Samuel Lapkin, David Scott, Jeff Kuan, Ashish D Diwan

European Spine Journal | SPRINGER | Published : 2019

Abstract

PURPOSE: Abnormal stress in the lumbar vertebra, also known as bony stress, can be a precursor to degenerative changes which may manifest as low back pain (LBP). However, the prevalence of bony stress in the lumbar spine and its relationship with degenerative changes and LBP is unclear. The purpose of this study was to evaluate the prevalence of bony stress in the lumbar spine and its relationship with intervertebral disc (IVD) degeneration, facet osteoarthritis and LBP in patients under 25 years of age. METHODS: A retrospective case-control study of 130 patients under 25 years of age was conducted from a population of 493 patients who had lumbar MRI across three imaging centres over three y..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council Australia Career Development Fellowship


Funding Acknowledgements

This work was supported by an Australian Government Research Training Program Scholarship and a University Postgraduate Award to KS, a National Health and Medical Research Council Australia Career Development Fellowship (GNT1123014) to DS, and internal research funds from Spine Service.