Journal article

Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR

EM Dunne, M Choummanivong, EFG Neal, K Stanhope, CD Nguyen, A Xeuatvongsa, C Satzke, V Sychareun, FM Russell

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2019

Open access

Abstract

Nasopharyngeal carriage of Streptococcus pneumoniae (the pneumococcus) is a precursor to pneumococcal disease. Several host and environmental factors have been associated with pneumococcal carriage, however few studies have examined the relationship between host factors and pneumococcal carriage density. We sought to identify risk factors for pneumococcal carriage and density using data from cross-sectional pneumococcal carriage surveys conducted in the Lao People's Democratic Republic before and after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13). Nasopharyngeal swabs were collected infants from aged 5-8 weeks old (n = 999) and children aged 12-23 months (n = 1,01..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

The project was funded by Gavi, the Vaccine Alliance (https://www.gavi.org/) and the World Health Organization Western Pacific Regional Office (https://www.who.int/westernpacific), with support from the Victorian Government's Operational Infrastructure Support Program (https://www2.health.vic.gov.au/about/clinical-trials-and-research/operationalinfrastructure-support).FMR was supported by a NHMRC Early Career and TRIP Fellowships (https://www.nhmrc.gov.au/).CS was supported by a NHMRC Career Development Fellowship (1087957) and a veski Inspiring Women Fellowship (https://www.veski.org.au/).EFGN holds an Australian Government Research Training Scholarship (https://www.education.gov.au/research-training-program).The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.