Prediction of adult class II/III obesity from childhood BMI: the i3C consortium.
Jessica G Woo, Nanhua Zhang, Matthew Fenchel, David R Jacobs, Tian Hu, Elaine M Urbina, Trudy L Burns, Olli Raitakari, Julia Steinberger, Lydia Bazzano, Ronald J Prineas, Cashell Jaquish, Markus Juonala, Justin R Ryder, Stephen R Daniels, Alan Sinaiko, Terence Dwyer, Alison Venn
International Journal of Obesity | Published : 2020
BACKGROUND AND OBJECTIVES: Adult class II/III obesity (BMI ≥ 35 kg/m2) has significant adverse health outcomes. Early prevention and treatment are critical, but prospective childhood risk estimates are lacking. This study aimed to define the prospective risk of adult class II/III obesity, using childhood BMI. METHODS: Children ages 3-19 years enrolled in cohorts of the International Childhood Cardiovascular Cohort (i3C) consortium with measured BMI assessments in childhood and adulthood were included. Prospective risk of adult class II/III obesity was modeled based on childhood age, sex, race, and BMI. RESULTS: A total of 12,142 individuals (44% male, 85% white) were assessed at median age 1..View full abstract