Journal article

Mechanisms of normal labour

Caitlyn Nguyen-Ngo, Martha Lappas

CURRENT OPINION IN PHYSIOLOGY | ELSEVIER | Published : 2020

Abstract

Human labor is a complex and highly regulated event, whereby high-intensity and high-frequency myometrial contractions are critical contributions to the expulsion of the fetus from the womb. Though the exact process of human labor is not yet defined, recent research has elucidated several key factors that contribute to uterine activation. In this review, we summarise the mechanisms of myometrial contractility at an organ, cellular and molecular level.

Grants

Funding Acknowledgements

Associate Professor Martha Lappas is supported by a Research Fellowship from the Department of Obstetrics and Gynaecology (University of Melbourne) and a Faculty Fellowship from the University of Melbourne. Caitlyn Nguyen-Ngo is supported by an Australian Government Research Training Program (RTP) Scholarship.