Inflammatory mediators are potential biomarkers for extracorporeal shockwave therapy in horses.
J-W Chen, D Stefanovski, J Haughan, Z Jiang, R Boston, LR Soma, MA Robinson
Equine Veterinary Journal | Published : 2020
BACKGROUND: Extracorporeal shockwave therapy (ESWT) can potentially mask painful injuries in equine athletes. Tests to detect whether a horse has received ESWT prior to competition are needed. Extracorporeal shockwave therapy is known to affect inflammatory mediators in other species, and if these mediators are altered in the horse, these could serve as biomarkers of ESWT. OBJECTIVES: To test the hypothesis that a single application of ESWT will alter the circulating protein concentrations of 10 inflammatory mediators in horse plasma. STUDY DESIGN: Prospective repeated measures experimental study. METHODS: Eleven healthy horses were administered a single dose of ESWT on the dorsal surface of..View full abstract