Associations between ethnicity, social contact, and pneumococcal carriage three years post-PCV10 in Fiji
Eleanor FG Neal, Stefan Flasche, Cattram D Nguyen, F Tupou Ratu, Eileen M Dunne, Lanieta Koyamaibole, Rita Reyburn, Eric Rafai, Mike Kama, Belinda D Ortika, Laura K Boelsen, Joseph Kado, Lisi Tikoduadua, Rachel Devi, Evelyn Tuivaga, Catherine Satzke, E Kim Mulholland, W John Edmunds, Fiona M Russell
Vaccine | ELSEVIER SCI LTD | Published : 2020
BACKGROUND: Pneumococcal carriage is a prerequisite for pneumococcal disease. Little is known about whether social contact frequency and intensity are associated with pneumococcal carriage. In Fiji, indigenous iTaukei have higher prevalence of pneumococcal carriage compared with Fijians of Indian Descent (FID). We hypothesised that contact differences may contribute to ethnic differences in pneumococcal carriage prevalence and density. METHODS: In 2015, young infants (5-8 weeks), toddlers (12-23 months), children (2-6 years), and caregivers from Suva and surrounding areas, participated in a cross-sectional survey (n = 2014), three years post pneumococcal conjugate vaccine introduction. Demog..View full abstract
Awarded by Bill & Melinda Gates Foundation
Awarded by Royal Society
This work was supported by the Bill & Melinda Gates Foundation [grant numbers OPP1126272 and OPP1084341], the Victorian Government's Operational Infrastructure Support Project, and the Department of Foreign Affairs and Trade of the Australian Government, the Fiji Health Sector Support Program. FHSSP was implemented by Abt JTA on behalf of the Australian Government. Fiona Russell held a National Health and Research Medical Council (NHMRC) Early Career Fellowship and NHMRC TRIP Fellowship; Catherine Satzke holds a NHMRC Career Development Fellowship and a Veski Inspiring Women Fellowship; Eleanor Neal holds an Australian Government Research Training Program Scholarship; Stefan Flasche is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (grant number 208812/Z/17/Z).