Journal article

Proinflammatory Diet Increases Circulating Inflammatory Biomarkers and Falls Risk in Community-Dwelling Older Men

Mavil May C Cervo, David Scott, Markus J Seibel, Robert G Cumming, Vasi Naganathan, Fiona M Blyth, David G Le Couteur, David J Handelsman, Rosilene Ribeiro, Louise M Waite, Nitin Shivappa, James R Hebert, Vasant Hirani

Journal of Nutrition | OXFORD UNIV PRESS | Published : 2020

Abstract

BACKGROUND: The relations between diet, chronic inflammation, and musculoskeletal health are unclear, especially among older men. OBJECTIVE: This study aimed to determine associations of the Dietary Inflammatory Index (DII) with inflammatory biomarkers, musculoskeletal health, and falls risk in community-dwelling older men. METHODS: The cross-sectional analysis included 794 community-dwelling men, mean age 81.1 ± 4.5 y, who participated in the 5-y follow-up of the Concord Health and Aging in Men Project. Of these, 616 were seen again 3 y later for the longitudinal analysis. Energy-adjusted DII (E-DII) was calculated from a validated diet history questionnaire. Bone mineral density (BMD) was ..

View full abstract

University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by National Health and Medical Research Council of Australia R.D. Wright Biomedical Career Development Fellowship


Funding Acknowledgements

The CHAMP study is funded by the National Health and Medical Research Council of Australia(project grant number: 301916) and the Aging and Alzheimer's Institute. The funding body had no role in the design and conduct of the study; collection, analysis, and interpretation of the data; preparation and review of the manuscript; or the decision to publish. DS is supported by a National Health and Medical Research Council of Australia R.D. Wright Biomedical Career Development Fellowship (1123014).