Journal article

Prevalence of suicide attempts in bipolar disorder: a systematic review and meta-analysis of observational studies

Min Dong, Li Lu, Ling Zhang, Qinge Zhang, Gabor S Ungvari, Chee H Ng, Zhen Yuan, Yifan Xiang, Gang Wang, Yu-Tao Xiang

Epidemiology and Psychiatric Sciences | CAMBRIDGE UNIV PRESS | Published : 2020

Abstract

AIMS: Bipolar disorder (BD) is a severe psychiatric disorder associated with a high risk of suicide. This meta-analysis examined the prevalence of suicide attempts (SA) in patients with BD and its associated factors. METHODS: A systematic literature search was conducted in the PubMed, PsycINFO, EMBASE and Web of Science databases from their inception to 11 June 2018. The prevalence of SA in BD was synthesised using the random-effects model. RESULTS: The search identified 3451 articles of which 79 studies with 33 719 subjects met the study entry criteria. The lifetime prevalence of SA was 33.9% (95% CI 31.3-36.6%; I2 = 96.4%). Subgroup and meta-regression analyses revealed that the lifetime p..

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University of Melbourne Researchers

Grants

Awarded by University of Macau


Awarded by National Key Research & Development Program of China


Awarded by Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support


Awarded by Beijing Municipal Administration of Hospitals' Ascent Plan


Funding Acknowledgements

The study was supported by the University of Macau (MYRG2015-00230-FHS; MYRG2016-00005-FHS), the National Key Research & Development Program of China (No. 2016YFC1307200), the Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (No.ZYLX201607) and the Beijing Municipal Administration of Hospitals' Ascent Plan (No. DFL20151801).