The bacterial SoxAX cytochromes
Ulrike Kappler, Megan J Maher
Cellular and Molecular Life Sciences | SPRINGER BASEL AG | Published : 2013
SoxAX cytochromes are heme-thiolate proteins that play a key role in bacterial thiosulfate oxidation, where they initiate the reaction cycle of a multi-enzyme complex by catalyzing the attachment of sulfur substrates such as thiosulfate to a conserved cysteine present in a carrier protein. SoxAX proteins have a wide phylogenetic distribution and form a family with at least three distinct types of SoxAX protein. The types of SoxAX cytochromes differ in terms of the number of heme groups present in the proteins (there are diheme and triheme versions) as well as in their subunit structure. While two of the SoxAX protein types are heterodimers, the third group contains an additional subunit, Sox..View full abstract
Awarded by Australian Research Council
This work was supported by a fellowship (Australian Research Fellowship, DP0878525) from the Australian Research Council to UK. MJM is supported by a La Trobe Institute for Molecular Science Senior Research Fellowship.