Journal article

The influence of sex and pre-operative obesity on biomechanics two years after total knee arthroplasty: A longitudinal cohort study

KL Paterson, L Sosdian, KL Bennell, BR Metcalf, T Wrigley, J Kasza, MM Dowsey, PF Choong, RS Hinman

Gait & Posture | ELSEVIER IRELAND LTD | Published : 2020


BACKGROUND: Sex and obesity may influence knee biomechanics associated with poor outcomes following primary total knee arthroplasty (TKA) however their long-term impact has not been investigated. RESEARCH QUESTION: Does sex and/or pre-operative obesity influence change in gait biomechanics from pre-TKA to two-years after TKA, and do knee biomechanics return to normal two-years after TKA? METHODS: In this longitudinal study, gait analysis was performed on 78 patients undergoing TKA for knee osteoarthritis prior to surgery (baseline), and on 66 (85 %) of these who returned at the two year follow-up. Gait biomechanics were also collected on a reference sample of 40 asymptomatic participants. Kn..

View full abstract

Related Projects (7)


Awarded by Australian Research Council

Awarded by NHMRC Principal Research Fellowship

Awarded by NHMRC Career Development Fellowship

Awarded by NHMRC Practitioner Fellowship

Awarded by NHMRC Senior Research Fellowship

Funding Acknowledgements

This study was supported by funding from the Australian Research Council (#LP120100019) in partnership with DePuy International. Kim Bennell holds an NHMRC Principal Research Fellowship (APP1058440). Michelle Dowsey holds an NHMRC Career Development Fellowship (APP1122526). Peter Choong holds a NHMRC Practitioner Fellowship (APP1154203). Rana Hinman holds an NHMRC Senior Research Fellowship (#1154217). The authors would like to acknowledge Jane Keenan for her assistance with coordinating the study and the following surgeons who performed the TKRs: Mr Dirk Van Bavel, Mr Audi Widjaja, Mr Altay Altuntas and Mr James Stoney.