Feeding supplemental 25-hydroxyvitamin D-3 increases serum mineral concentrations and alters mammary immunity of lactating dairy cows
Michael B Poindexter, Mercedes F Kweh, Roney Zimpel, Jorge Zuniga, Camilo Lopera, Marcos G Zenobi, Yun Jiang, Mark Engstrom, Pietro Celi, Jose EP Santos, Corwin D Nelson
Journal of Dairy Science | ELSEVIER SCIENCE INC | Published : 2020
Objectives were to determine the effects of feeding supplemental 25-hydroxyvitamin D3 [25(OH)D3] on concentrations of vitamin D metabolites and minerals in serum, mammary immune status, and responses to intramammary bacterial infection in dairy cows. Sixty multiparous, pregnant lactating Holstein cows with somatic cell count <200,000/mL were blocked by days in milk and milk yield and randomly assigned to receive a daily top-dressed dietary supplement containing 1 or 3 mg of vitamin D3 (1mgD or 3mgD), or 1 or 3 mg 25(OH)D3 (1mg25D or 3mg25D) for 28 d (n = 15/treatment). Cows were kept in a freestall barn and fed a total mixed ration in individual feeding gates. Individual dry matter intake (D..View full abstract
The authors thank Wayne Garcia, Natalie Cleghorn, Madelin Pozadas, Teri Williams (University of Florida, Gainesville) and Anastasia Meredith (Florida A&M University, Tallahassee) for technical assistance. Funding was provided from the Milk Checkoff Board of Southeast Milk Inc. (Belleview, FL) and DSM Nutritional Products (Kaiseraugst, Switzerland).