Journal article
Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4
RH Guymer, PJ Rosenfeld, CA Curcio, FG Holz, G Staurenghi, KB Freund, S Schmitz-Valckenberg, J Sparrow, RF Spaide, A Tufail, U Chakravarthy, GJ Jaffe, K Csaky, D Sarraf, JM Monés, R Tadayoni, J Grunwald, F Bottoni, S Liakopoulos, D Pauleikhoff Show all
Ophthalmology | ELSEVIER SCIENCE INC | Published : 2020
Abstract
Purpose: To describe the defining features of incomplete retinal pigment epithelium (RPE) and outer retinal atrophy (iRORA), a consensus term referring to the OCT-based anatomic changes often identified before the development of complete RPE and outer retinal atrophy (cRORA) in age-related macular degeneration (AMD). We provide descriptive OCT and histologic examples of disease progression. Design: Consensus meeting. Participants: Panel of retina specialists, including retinal imaging experts, reading center leaders, and retinal histologists. Methods: As part of the Classification of Atrophy Meeting (CAM) program, an international group of experts analyzed and discussed longitudinal multimod..
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Awarded by Macula Foundation
Funding Acknowledgements
Acquisition of human donor eyes and the Project MACULA website were supported by the National Institutes of Health, Bethesda, Maryland (grant nos.: R01EY06019 [C.A.C.] and P30 EY003039 [C.A.C.]), the National Institutes of Health (grant nos.: R01EY024091 [J.S.], R01EY12951 [J.S.], R24 EY027285 [J.S.], and P30EY019007 [J.S.]); EyeSight Foundation of Alabama (C.A.C.); International Retinal Research Foundation (C.A.C.); the Edward N. and Della L. Thome Foundation (C.A.C.; J.S.); the Arnold and Mabel Beckman Initiative for Macular Research (C.A.C.; J.S.); Research to Prevent Blindness, Inc, New York, New York (C.A.C., J.S.); the Lowy Research Medical Institute (A.C.B.); the National Health & Medical Research Council of Australia (fellowship no.: GNT1103013 [R.H.G.]); Foundation Fighting Blindness (J.S.); and the National Institute for Health Research Biomedical Research Centre Moorfields Eye Hospital, London, United Kingdom (A.T.). Clinicopathologic correlation supported by the Macula Foundation, New York (C.A.C.).